SCIENTIFIC PROGRAM

The preliminary schedule for the Congress includes space for 3 pre-congress meetings, 7 keynote conferences, 8 parallel joint conferences, 20 parallel symposia, 12 parallel oral sessions, 5 poster sessions, 2 award conferences, and 4 short courses—totaling over 60 different activities. These events will range from scientific discussions to networking opportunities, all conducted in a setting designed to promote engagement and collaboration.

MAIN TOPICS

Explore the cutting-edge thematic axes that will define our congress’s dynamic scientific program! Crafted by the Scientific Committee, these exciting topics set the stage for groundbreaking discussions and innovations. From the latest advancements in early life health to the impacts of environmental changes and public health policies, our program promises to deliver compelling insights and foster impactful exchanges. Stay tuned as we delve into these pivotal areas, ensuring a congress experience brimming with discovery and inspiration.

01. Impact of Preconceptional Maternal and Paternal Health and Lifestyles on Offspring Health Throughout the Life Cycle.

The impact of preconceptional maternal and paternal health and lifestyles on offspring health throughout the life cycle encompasses several critical subtopics. These include reproductive health, the quality of gametes and germ cells, and the influence of maternal and paternal nutrition. Physical activity before and during pregnancy, as well as mental health, play significant roles. Preconceptional conditions like obesity, type 2 diabetes, hypertension, and renal disease, along with early life stressors such as lack of social support, discrimination, and violence, are also key factors. Additionally, unhealthy lifestyles involving tobacco, alcohol, cannabis, and other drugs, the influence of Assisted Reproductive Technologies, the maternal microbiome, and the consumption of ultra-processed foods will be considered.

02. Structure and Function of the Placenta as a Regulator of Health in the Next Generation.

The structure and function of the placenta as a regulator of health in the next generation are pivotal. The placenta plays a crucial role in normal pregnancy and pregnancy complications and significantly impacts the offspring’s health. Placental dysfunction can lead to alterations in the offspring, affecting vascular, renal, neurological, and other systems. Molecular markers, including omics data, can reveal insights into placental conditions in high-risk pregnancies and their implications for child health. Additionally, the expression and function of transport systems within the placenta are vital for nutrient and waste exchange. The role of placental and umbilical cord-derived progenitor cells, including their lineage commitment, also contributes to understanding how placental health influences the development and well-being of the next generation.

03. Mechanisms Determining Transgenerational Effects of Health and Disease.

Mechanisms determining transgenerational effects of health and disease involve a complex interplay of genetics and epigenetics, which shape health outcomes across generations. The setting of microbiomes—such as gut, skin, and airway—also plays a critical role in these effects. Metabolic health, alongside maternal and infant immune systems, cardiovascular health, neurodevelopment, and bone health are key areas of focus. Advances in metabolomics, lipidomics, and proteomics, as well as innovative technologies like organoids, tissue transcriptomics, and single-cell analysis, provide deeper insights into these mechanisms. Novel technologies in reproductive health further enhance our understanding of how these factors influence transgenerational health and disease.

04. Role of Infant and Young Child Feeding Practices on Long-Term Health

Maternal-fetal, infant, and young child feeding practices play a critical role in shaping long-term health outcomes. Breastfeeding, with its unique immune properties and optimal balance of macro and micronutrients, supports the development of a robust immune system and a healthy gut microbiome. The composition of breastmilk not only nurtures but also fosters essential mother-infant bonding, which is vital for emotional and psychological development. While formula feeding provides a necessary alternative, it lacks some of the immunological benefits and microbiome support offered by breastmilk. The choice of feeding practices can therefore have lasting effects on the child’s health trajectory, influencing everything from immune function to metabolic health and overall well-being.

05. Impact of Early Life Exposures and Environmental Pollutants on Lifelong Health and Intergenerational Outcomes.

Early life exposures, including environmental pollutants, have profound and lasting effects on future generations. This encompasses a range of factors such as pandemics, infections, migration, and food insecurity, including the consumption of ultra-processed foods and deficiencies in micronutrients. Additionally, exposure to war, drugs, alcohol (such as Fetal Alcohol Spectrum Disorders), substance abuse, and vaping, alongside maternal mental health issues and chronic maternal-fetal hypoxia, can significantly impact long-term health outcomes. Environmental pollutants like pesticides, heavy metals (e.g., mercury), bisphenol A, microplastics, plasticizers, and polycyclic aromatic hydrocarbons further compound these effects. The exposome—encompassing the totality of environmental exposures throughout an individual’s life—plays a critical role in shaping health across generations.

06. Plant and Animal Health and Its Impact on Reproductive Age Individuals and Their Offspring

The health of plants and animals is intricately linked to the well-being of people and the environment, with significant implications for individuals of reproductive age and their offspring. Health threats such as COVID-19, Zika virus, Dengue fever, and Avian flu can directly impact reproductive-age individuals and potentially affect their future generations. Understanding the Developmental Origins of Health and Disease (DOHaD) concept is crucial in animal production, as it highlights how early-life conditions influence long-term health outcomes. Moreover, the interaction between animal production and ecosystem health underscores the importance of maintaining a balanced environment to support both animal health and human health. This holistic approach ensures that the interconnected systems of plant and animal health, human well-being, and ecosystem sustainability are all considered in addressing and mitigating health risks.

07. Effects of Environmental Climate Change on Early Life Health Setting in Future Generations.

The impact of preconceptional maternal and paternal health and lifestyles on offspring health throughout the life cycle encompasses several critical subtopics. These include reproductive health, the quality of gametes and germ cells, and the influence of maternal and paternal nutrition. Physical activity before and during pregnancy, as well as mental health, play significant roles. Preconceptional conditions like obesity, type 2 diabetes, hypertension, and renal disease, along with early life stressors such as lack of social support, discrimination, and violence, are also key factors. Additionally, unhealthy lifestyles involving tobacco, alcohol, cannabis, and other drugs, the influence of Assisted Reproductive Technologies, the maternal microbiome, and the consumption of ultra-processed foods will be considered.

08. Interventional strategies to prevent late-life outcomes resulting from early-life insults

The impact of preconceptional maternal and paternal health and lifestyles on offspring health throughout the life cycle encompasses several critical subtopics. These include reproductive health, the quality of gametes and germ cells, and the influence of maternal and paternal nutrition. Physical activity before and during pregnancy, as well as mental health, play significant roles. Preconceptional conditions like obesity, type 2 diabetes, hypertension, and renal disease, along with early life stressors such as lack of social support, discrimination, and violence, are also key factors. Additionally, unhealthy lifestyles involving tobacco, alcohol, cannabis, and other drugs, the influence of Assisted Reproductive Technologies, the maternal microbiome, and the consumption of ultra-processed foods will be considered.

09. Big Data and Cohorts in DOHaD Research.

The impact of preconceptional maternal and paternal health and lifestyles on offspring health throughout the life cycle encompasses several critical subtopics. These include reproductive health, the quality of gametes and germ cells, and the influence of maternal and paternal nutrition. Physical activity before and during pregnancy, as well as mental health, play significant roles. Preconceptional conditions like obesity, type 2 diabetes, hypertension, and renal disease, along with early life stressors such as lack of social support, discrimination, and violence, are also key factors. Additionally, unhealthy lifestyles involving tobacco, alcohol, cannabis, and other drugs, the influence of Assisted Reproductive Technologies, the maternal microbiome, and the consumption of ultra-processed foods will be considered.

10. Public Health Policies Across the Life Cycle.

Public health policies across the life cycle are essential for shaping health outcomes from preconception through old age. These policies encompass regulations related to the production, distribution, and sale of food, as well as measures addressing climate change. Government actions, including taxes, food labeling, and other regulations, play a crucial role in promoting health. Special attention to public health policies during the preconception stage and ongoing education and science communication about transgenerational health are vital. Additionally, addressing the health impacts of forced migration and considering cultural practices, particularly within indigenous populations, are important for holistic health care. Integrating these elements into health care systems can improve long-term health outcomes and equity across the life course.

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SCIENTIFIC ORGANIZATION

KCL Dept Women and Children’s Health
10th Floor, North Wing,
St Thomas’ Hospital
Westminster Bridge Road
London SE1 7EH

SCIENTIFIC ORGANIZATION

Latin American DOHaD Regional Society
sec.la.dohad@gmail.com
www.ladohadsociety.com/

GENERAL ORGANIZATION

MET GROUP
Av. Cabildo 642 · Piso 11° · CABA · Argentina
Tel: (+5411) 5263·3·MET (638)
info@metgroup.com.ar
www.metgroup.com.ar

DOHAD

LA-DOHAD